AUSTRALIA - Celltrion Healthcare and Juno Pharmaceuticals Partnership

SYDNEY, AUSTRALIA – Celltrion Healthcare Australia (Celltrion) and Juno Pharmaceuticals (Juno) have entered in to a co-marketing partnership, covering the biosimilar products Herzuma (biosimilar trastuzumab), and Truxima (biosimilar rituximab). Celltrion Healthcare Australia, a division of the biosimilar developer Celltrion Healthcare, are the Marketing Authorisation holders in Australia for these and other biosimilar brands and will distribute the products in the market. Juno as a leading supplier into hospitals, has been appointed to provide sales promotion and hospital contracting services to Australian Hospital market customers.

Commenting on this partnership, Cecilia Sung – Country Manager ANZ stated that Celltrion Healthcare Australia is pleased with the opportunity to partner with Juno Pharmaceuticals to offer our global biosimilar brands to Australian Healthcare professionals and patients, with a blend of quality & economic benefits. We are also confident that with an extensive commercial network, strong customer relationships and established hospital market presence by Juno Pharmaceuticals, Biosimilar brands from Celltrion Healthcare will achieve high customer acceptance as they have been in regulated markets such as EU/ USA.

“We are excited that Celltrion has chosen Juno to represent their rituximab and trastuzumab products in Australia. The Juno team has very extensive experience with biosimilars in the Australian marketplace over the last decade” says Mark Crotty, CEO Juno Australia.

AUSTRALIA - Juno Pharmaceuticals Acquires Noradrenaline 2 mg/2 mL & 4 mg/4 mL from Mayne Pharma

MELBOURNE, AUSTRALIA – Juno Pharmaceuticals is pleased to announce the acquisition of noradrenaline 2 mg/2 mL and 4 mg/4 mL concentrated injection from Mayne Pharma; an important addition to Juno’s growing range of vasopressors and critical care medicines.

As part of the acquisition, Juno will receive the intellectual property and regulatory approvals for NORADRENALINE MYX 2 mg/2 mL concentrated solution for injection ampoule and NORADRENALINE MYX 4 mg/4 mL concentrated solution for injection ampoule, along with associated contracts and agreements.

This acquisition is Juno’s second for 2019 and is another milestone in Juno’s continued growth and vision to be the leader in supply of off-patent products in hospitals across Australia and New Zealand.

Our focus on hospital injectable medicines and hospital customers makes us ideally placed to supply this product in the Australian market, noted Juno CEO & Managing Director, Mark Crotty. It is exciting to see our range of hospital products growing rapidly, customers see us as their trusted partner in this area.

The agreement comes into effect on July 16th, 2019 and Juno’s Key Account Managers will work closely with customers and wholesalers to ensure a smooth transition and continuity of supply. As with all Juno products, continuous, reliable supply is a top priority.

From July 16th, 2019, all commercial enquiries regarding noradrenaline should be directed to your local Juno representative. Any adverse event reporting, product complaints and medical enquiries should directed to Juno Medical Information on 1800 620 076 ormedical-enquiries@www.junopharm.com.au

AUSTRALIA - Juno Acquires Local Portfolio of Essential Injectable Medicines from AstraZeneca

MELBOURNE, AUSTRALIA – Juno Pharmaceuticals Pty Ltd is pleased to announce the acquisition of a local portfolio of essential injectable medicines from AstraZeneca Pty Ltd.  This acquisition will see Juno’s product range grow to over 60 molecules, focussed mainly in the hospital segment.

As part of the acquisition, Juno will receive the intellectual property and regulatory approvals for ten products (eight unique molecules), along with associated contracts and agreements.

This acquisition is the second Juno has made since commencing sales in 2015 and is another milestone in Juno’s continued growth and vision to be the leader in supply of off-patent products in hospitals across Australia and New Zealand.

These critical medicines play a vital role in patient care in Australian and New Zealand hospitals. Our focus at Juno is to build a compelling portfolio that meets the local and unique needs of Australian and New Zealand hospitals, noted Juno CEO & Managing Director, Mark Crotty.

The agreement comes into effect on April 1st, 2019 and Juno’s key account managers will work closely with customers and wholesalers to ensure a smooth transition.

From April 1st, 2019, all commercial enquiries regarding the products below should be directed to your local Juno representative.  Any adverse event reporting, product complaints and medical enquiries should directed to Juno Medical Information on 1800 620 076 or medical-enquiries@www.junopharm.com.au

About Juno

Juno Pharmaceuticals is a rapidly growing, local Australian and New Zealand business and are experts in off-patent prescription pharmaceuticals. Juno’s portfolio includes medicines across a diverse range of therapeutic areas, with hospital products the core focus of the business. The acquisition of this portfolio is in line with Juno’s mission to improve the health of society, through delivering high quality products to patients, and value to hospitals, the government and tax payers.

About AstraZeneca

AstraZeneca is a global, science-led biopharmaceutical company that focuses on the discovery, development and commercialisation of prescription medicines, primarily for the treatment of diseases in three therapy areas – Oncology, Cardiovascular, Renal & Metabolism and Respiratory. The Company also is selectively active in the areas of autoimmunity, neuroscience and infection. AstraZeneca operates in over 100 countries and its innovative medicines are used by millions of patients worldwide.

For more information, please visit www.astrazeneca.com and www.astrazeneca.com.au.

AUSTRALIA - Juno Pharmaceuticals and Amgen Australia announce partnership for the marketing and distribution of biologic medicines Neulasta® (Pegfilgrastim) and Ristempa® (Pegfilgrastim) in Australia

MELBOURNE, AUSTRALIA – Juno Pharmaceuticals is pleased to announce that Amgen Australia have appointed us as their distribution partner for the exclusive marketing and distribution of 291 Amgen’s biologic medicines Neulasta (Pegfilgrastim) and the launch of Ristempa (Pegfilgrastim). This will be effective 1 March 2018.

Under the terms of this agreement, Juno will be responsible for the commercial management of these brands in Australia. Amgen will continue to be the sponsor of these brands on the Australian Register of Therapeutic Goods (ARTG) and there will be no changes to the product, packaging, labelling and wholesale distribution of Neulasta. We will ensure there is no interruption to the service provided, and your local Juno Key Account Manager will work with you to provide a smooth transition.

Juno Pharmaceuticals is a rapidly growing, local Australian and New Zealand business with expertise in both biosimilars and off patent medicines. Members of the Juno team have had previous experience in the launch and management of a number of biosimilars both in Australia and abroad, including the first and leading biosimilar filgrastim in Australia. Juno’s current portfolio includes medicines across a diverse range of therapeutic areas, with hospital products the core focus of the business and a strong pipeline of complex molecules.

This partnership is a major milestone in Juno’s continued growth and strategy of diversification and expansion into the biologic and biosimilar markets. The partnership is also in line with Juno’s mission to improve the health of society, through delivering high quality products to patients, and value to hospitals, the government and tax payers.

EUROPE - Speciality European Pharma Limited to rebrand as Contura in order to consolidate its corporate structure and drive growth

Speciality European Pharma Limited (“SEP”), the parent of a European healthcare group, is pleased to announce the rebranding of itself and each of its subsidiaries as Contura (“the Group”). The rebrand will consolidate the Group under a single corporate identity and positions it for future growth.

“I am pleased to see Contura moving into the next stage of its development, consolidating its position as a leading manufacturer and distributor of speciality medical device and pharmaceutical products. Contura has grown rapidly over recent years and I look forward to our journey as we continue to build on our existing products whilst expanding into new therapy areas with our hydrogel platform. With the recent filing of our premarket approval application for Bulkamid in the United States we also anticipate significant geographic expansion for our products in the years ahead.”

Patrick Banks, Chief Executive Officer.

About SEP and Contura

The Group specialises in the distribution and sale of healthcare products, both pharmaceuticals and medical devices, focused primarily in the fields of urology and urogynaecology. Its lead products are:

Bulkamid®

Aquamid®

Mitem®

Regurin® XL

Cystistat®

The Group was founded in 2000 and has built an experienced and accomplished management team. It came together as a result of SEP’s acquisition of Contura A/S, a Danish company based in Copenhagen, in 2013. Contura A/S had two marketed products at the time of its acquisition, Bulkamid® and Aquamid® . It also had a number of development programmes focused on additional uses of its hydrogel technology.

In prospect, the opportunities for new products include:

• approval of Bulkamid® in the United States (stress urinary incontinence)

• approval of Arthrosamid® in the EU (synovial implant for osteoarthritis)

• approval of Bulkamid® VUR in the EU and other territories (vesicoureteral reflux)

The Group has an established sales and marketing infrastructure in the leading European markets, either through its own sales force or through distribution partners. It has offices in the UK, Denmark, Germany, France and Italy and employs some 45 staff Europe wide.

Contact Patrick Banks, CEO

1Phone number: +44 (0)20 7421 7400

Please visit our rebranded web page for further information:

www.contura.com

AUSTRALIA - Juno Acquires Amneal Hospital Product Portfolio

Juno Pharmaceuticals announced today that it has acquired Amneal Pharmaceuticals’ injectables, ophthalmic, and oncology product portfolios in Australia.

“Juno is excited to add the Amneal Australia hospital injectable, ophthalmic, and oncology range to its growing portfolio. This Amneal portfolio complements many of Juno’s existing assets nicely and Juno is particularly excited to be managing products such as Bicnu (carmustine),” said CEO and Managing Director of Juno Australia, Mark Crotty.

Juno is a rapidly-growing local Australian business that recorded its first full year of commercial sales in 2016. Juno’s business model is based on partnering across all stages of the commercial cycle and has a core focus on local Australian hospital customer needs. The acquisition of Amneal’s portfolio is Juno Australia’s first since its formation in 2013 and when added to its existing product portfolio and strong pipeline, the acquisition is expected to position Juno as one of the largest generic injectable product hospital suppliers in the Australian market.

The acquisition takes effect from August 31st, 2017. Juno will work with Amneal to ensure a smooth transition of the business with suppliers and customers.

For all queries please contact:

Mark Crotty, +61 424 152 881